Sentence examples for recapitulating characteristics of from inspiring English sources

Mouse studies revealed a similar result when animals expressing the polyQ expanded exon 1 of huntingtin (Htt) showed a progressive neurological phenotype recapitulating characteristics of HD.

For example, tumors classified as a hormone-receptor positive subtype express estrogen receptor (ER or Esr1) and are generally dependent on estrogen for growth, recapitulating characteristics of a subset of normal, luminal epithelial cells found in the breast [ 6].

Artificial muscles recapitulated characteristics of human skeletal muscle tissue and could be implanted into immunodeficient mice.

Cell lines established from OS recapitulated characteristics of the primary tumor, including the expression of mature OB markers and ability to form mineralized tumors when transplanted.

Of note, all clonally expanded cells recapitulated characteristics of the CMS-induced cells consistent with stochastic adaptation rather than the selection of a pre-existing subpopulation of MDA-MB-231 cells.

These models recapitulate characteristics of MM; however, they are technically challenging and time consuming with long latency times and do not allow for evaluating multiple gene functions at a time.

We generalize this notion for protein interaction networks as follows to better recapitulate characteristics of the groups being compared to.

To interpret the observed amount of overlap, we performed extensive simulations that recapitulate characteristics of the three aCGH chips and distribution of log2 values (see Methods).

More importantly, these compounds show cellular activity by suppressing the H4K20me1 mark of SETD8 and recapitulate characteristic S/G2/M-phase cell cycle defects as observed for RNAi-mediated SETD8 knockdown.

Here we report that Atrx loss recapitulates characteristic disease phenotypes and molecular features in putative glioma cells of origin, inducing cellular motility although also shifting differentiation state and potential toward an astrocytic rather than neuronal histiogenic profile.

Genetic animal models recapitulating specific characteristics of the human condition have helped elucidate gene function and the genetic basis of disease.