Sentence examples for recapitulating both from inspiring English sources

In addition, we describe robust gene-interaction networks recapitulating both protein complexes and functional cooperation among complexes and pathways.

By recapitulating both the underlying genetics and the characteristic tumor-stroma microenvironment of brain cancer, genetically engineered mouse models (GEMMs) may offer distinct advantages over cell culture and xenograft systems in the preclinical testing of promising therapies.

Animal models recapitulating both ocular and neurological phenotypes of WARBM are required in order to investigate the ultrastructural and molecular aspects of disease pathogenesis that cannot be identified through examination of the affected individuals.

To explore a functional role of fascin, we used a mouse model of pancreatic cancer (KPC mice) recapitulating both pre-invasive PanIN (grade 1−3) and invasive, metastatic PDAC.

The model presented here is, to the best of our knowledge, the first analytical model of the yeast cAMP-PKA pathway that is capable of recapitulating both the short-term and long-term dynamics of cAMP signaling in wilde-type cells.

Hicks's outrage, bewilderment, and obsession is evident in a thirty-nine-page letter that he sent to me three months later, which recapitulates both his routine and the media politics going on around it.

This model uses the spontaneously immortalized human keratinocyte cell line NIKS and recapitulates both the three-dimensional microenvironment and epithelial mesenchymal interactions found in intact human skin.

This method of irreversible inactivation recapitulates both the lethal phenotype and the key molecular signatures that result from genetically disrupting Kin28 function in vivo.

The following chapter aims to introduce and discuss 3D cell-based in vitro models that recapitulate both the architecture and multicellular complexity of an organ/tumor in vivo but at the same time accommodate systematic experimental intervention.

This study has demonstrated that the PCL/zein-CL composite provides a simple platform to fabricate a new biomimetic scaffold for bone tissue engineering, which can recapitulate both the morphology of extracellular matrix and composition of the bone.

The objective of this study was to recapitulate both the ECM composition and mechanical properties of adipose tissue in vitro to stimulate adipogenesis of human adipose-derived stem cells (ASCs) in the absence of exogenous adipogenic growth factors and small molecules.