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The transition from preconfluent to confluent cell cultures recapitulates the development of epithelial cell polarity and concomitant sequestering of proteins to specific membrane domains [53].
Fusarium wilt of A. thaliana recapitulates the development of disease symptoms in field hosts [ 1].
The DMBA/TPA two-stage model for skin squamous cell carcinoma (SCC), which recapitulates the development of human skin SCC, is the most commonly used model.
These data describe a novel hetero-transplantation tumor model that exhibits a metastatic profile that recapitulates the development of metastasis in human breast cancer patients.
Wound healing takes place on the pedicle stumps immediately after casting, following which regeneration of antlers ensues in a process that recapitulates the development of the first antlers [ 34, 35]).
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This indicates that the pre-clinical model of induction therapy that we have developed in this study can effectively recapitulate the development of clinical drug resistance.
Herein, we further report that a subset of cysts in this amniogenic 3D culture system appear to recapitulate the development of the human amniotic sac.
In this review, we will recapitulate the development of antibody-based therapy, and detail recent advances and new functions, particularly in the field of cancer immunotherapy.
If we recapitulate the development of evolutionary thinking from Darwin through the Modern Synthesis into the age of genomes, we see that genomes have provided major bodies of evidence for the prevalence of vertical descent among multicellular eukaryotes, with sexual recombination, mutation, gene and genome duplications being the main processes that give rise to genetic novelty.
To clarify the role of HFD during hepatocarcinogenensis, we have established an animal model of HCC using the classic hepatic carcinogen diethylinitrosamine (DEN) in rats chronically fed high-saturate-fat diet to experimentally recapitulate the development of liver cancer in the setting of fatty liver disease, and to understand the possible mechanisms therein.
We have now extended these observations in a different transgenic AD model, i.e. Tg APParc mice that recapitulates the stereotypic development of AD pathology, and have used a different approach (excitotoxin-induced lesion) to destroy projecting neurons, assessing both up and downstream connecting brain regions.
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