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Murine models of infection recapitulate a number of key features of the human disease and allow the use of genetically modified bacteria and hosts to identify determinants of pathogenicity and susceptibility.
Our results recapitulate a number of earlier findings [ 25], in a fully automated fashion, with many more genomes and miRNAs.
The model is able to recapitulate a number of pathologies observed in human mitochondrial disease, including disrupted mitochondrial function, abnormal mitochondrial morphology and decreased exercise ability.
These results indicate that mammary tumors in the SRC1-/- neu mouSRC1-/- neulate a number of gene expreSRC1-/- neues in humouserecapitulate.
Because zebrafish embryos are transparent and their genetic manipulation is straightforward, the zebrafish has been used to recapitulate a number of cardiovascular disease processes ranging from congenital heart defects to arrhythmia to cardiomyopathy.
Although there may be slight differences in folding between reconstituted half-molecule transporters and full-length wt hRFC, wt-N6/C6 hRFC was shown to accurately recapitulate a number of functional characteristics of full-length wt hRFC [ 20].
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Gilbert recapitulates a number of his earlier themes, including the satire of class distinctions figuring in many of his earlier librettos.
This mouse recapitulates a number of pathological features of the Fragile X Full Mutation, such as macroorchidism and abnormal dendritic arborization in the brain.
The role of DNA damage resulting in accelerated aging has been recapitulated in a number of mouse models (reviewed by Schumacher et al. [ 32]).
In animal models, microcephaly is defined as a reduced brain size and it has been recapitulated in a number of genetic mouse models as well as by prenatal exposure to ionizing radiation (Kitamura et al., 2001; Sun et al., 1995).
Understanding tissue morphogenesis in the Xenopus laevis model system is of significant value because the relevant signaling networks and cell behaviors are recapitulated in a number of mammalian developmental and growth processes, such as angiogenesis, wound healing, and tumor growth [ 6- 8].
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