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We reasoned that sequence divergence in L2 epitopes rather than the lack of proper display of those epitopes could explain the lack of cross-neutralization.
We reasoned that sequence coverage differences between the two exome groups may contribute to the contrast in short CNV detection.
Due to methodological reasons sequence analyses of the entire HBV genome were performed by direct sequencing.
For this reason, sequence similarity is considered the primary marker of homology.
For these reasons, sequence census technologies will provide powerful and versatile tools to study post-transcriptional processing of genetic sequences.
For this reason, sequence comparisons are generally performed by heuristics like BLAST (Altschul et al., 1997) and FASTA (Pearson, 1990), which have proved to be quite effective and significantly faster than the dynamic programming algorithms.
For this reason sequences that were not observed multiple times were removed from the database in curation.
For this reason, sequences were aligned both to a reference transcript database (for estimation of expression of well-annotated transcripts) and to the human genome (for estimation of total expression of all exons, whether annotated or not).
For various reasons, sequencing of an appropriate control sample is not always possible.
For unknown reasons, sequencing was not successful for all individuals from each site.
For these reasons, sequencing of the cucumber genome and the development of functional genomic tools are of great importance.
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CEO of Professional Science Editing for Scientists @ prosciediting.com