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Overall, the treatments were reasonably tolerated.
Perampanel is well tolerated at 4 mg and reasonably tolerated at 8 and 12 mg.
Addition of an oxygen atom (in 51) was reasonably tolerated (sevenfold loss in activity).
TAS-106 was reasonably tolerated in patients with platinum-failure HNSCC and NPC.
The safety analysis showed that perampanel was well tolerated at 4 mg and reasonably tolerated at 8 and 12 mg.
In the more modern clinical setting 300 mg/day of quinacrine has been administered and found to be reasonably tolerated with no reported incidence of hematologic toxicity [ 66].
Similar(49)
According to the court of appeal, the question then becomes whether or not they can "reasonably tolerate" this suppression of their identity.
The paper begins by reviewing qualitative criteria that are evaluated to determine what amount of risk can reasonably be tolerated.
All four regimens of ganciclovir were reasonably well tolerated, with safety profiles similar to what has been reported in prior work.
Based on the analysis of a large database of >1,500 patients included in four randomised, double-blind, placebo-controlled trials, topiramate was generally safe and reasonably well tolerated in migraine prevention [27].
Similar results were also found after propensity score matching.Although experience of using rt-PA in patients with ischemic stroke on a NOAC is limited, these preliminary observations suggest that rt-PA appears to be reasonably well tolerated without prohibitive risks for adverse events among selected NOAC-treated patients.
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CEO of Professional Science Editing for Scientists @ prosciediting.com