Manufactured drama around something life and death with the potential to be harmful to the person who doesn't know and reasonably should, is deeply problematic.
However, compounds 8, 26, and 71 are reasonably metabolically stable, suggesting nothing fundamentally problematic with these scaffolds in terms of cytochrome P450-driven metabolism.
For new prescriptions, electronic data are reasonably reliable, but attribution may still be problematic because, although the GP who signs the prescription takes legal responsibility for it, many drugs are initiated on specialist recommendation.
While quantifying a "troglomorphy index" is reasonably straightforward, quantifying time available for evolution is more problematic, for several reasons.
Such reflection quickly reveals the extent to which various aspects of morality might reasonably be seen as both intellectually and practically problematic.
Her kidneys are ruined; her gut is problematic, she had bleeding; her lungs are reasonably O.K.; she's got calcification in her skin; her vessels leak".
We can reasonably suppose, however, that the assembly of this segment was problematic, thus providing a paradigmatic example of how assembly work can take advantage of the FISH approach.
The Central Intelligence Agency reasonably and objectively assessed in Iraqi Support for Terrorism that the most problematic area of contact between Iraq and Al Qaeda were the reports of training in the use of nonconventional weapons, specifically chemical and biological weapons.
Some atheists think that the reference range of "God" is so indeterminate and the concept of God so problematic that it is impossible for someone fully aware of that reasonably to believe in God; believers, by contrast, think that, though the reference range of "God" is indeterminate, it is not so indeterminate and the concept of God so problematic as to make belief irrational or incoherent.
Ironically, getting an early offer can be problematic: Once a company has made an offer, it will expect an answer reasonably soon.
According to a reasonably charitable assessment, the best of Ryle's lessons has long been assimilated while the problematic has been discarded.
