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However, it appears not to be suitable for viral population assembly as when applied to current samples, it generated an excessive number of contigs, which cannot be reasonably handled.
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Scandalously thick and rich, it was more sandwich than anyone can reasonably handle, and I bet no one leaves so much as a crumb or rivulet.
According to Nickolas Papadopoulos, director of translational genetics at the Ludwig Center at Johns Hopkins, professor of oncology at Johns Hopkins Medical Institutes, and coauthor of the study: Safe-SeqS enables researchers to extend the capacity of dPCR to many more loci up to 30 or more than BEAMing can reasonably handle.
"How the officer feels, what he thinks he can reasonably handle by himself, the level of threat.
Such excess raises the question -- How many friendships -- real, virtual or a combination of the two -- can any one person reasonably handle?
Next thing you know, you're pouring boxed red wine into a dirty paper cup in a grocery store parking lot because shopping seems like more than you can reasonably handle sober.
You may need to experiment a little to learn how much you can reasonably handle at a time.
On the other end of the spectrum, you don't want to overload yourself with classes, especially not before you know how many units you can reasonably handle during a given term.
They are not among academic offenses, like cheating or plagiarism, that might reasonably be handled by academic authorities.
The mix of minimal staging and vivid cinematic imagery was reasonably slickly handled, despite a certain early Doctor Who air to some of the more clumsy interactions.
With about four more plot lines than can reasonably be handled in a two-and-a-half hour long film, skimpy character development, and writing that verges on Hallmark-branded schmaltz, it can feel curiously devoid of subtlety.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com