In response to the patent awarded to the Broad Institute, the University of California has initiated 'interference proceedings' — a patent priority contest — saying that the use of CRISPR Cas9 in human cells was reasonably self-evident from Charpentier and Doudna's 2012 paper.
"It's reasonably self-evident that they will buy a lot more bread and a lot fewer cellphones," said Raymond Fisman, an assistant professor of economics at Columbia University's Graduate School of Business.
But the areas in which the action take place are reasonably confined and self-evident, and loaded with useful scenic appliances, and there are rarely time pressures so you can watch the same guard complaining about the heat for 20 minutes if you like.
She describes his discussion of sexual selection in The Descent of Man, which treats female sexual selection in animals but not in humans, comments reasonably that "for Darwin it was self-evident that in civilised regimes men did the choosing" and concludes slightly unfairly that "for him, Victorian males set the evolutionary compass".
It is evident that the model gives a reasonably good fit to the observed intensity profile for the Northern parts of the halo.
A reasonably high equitability of resource apportionment among species is evident as the resource distribution in the community follows a lognormal pattern.
Thus, adaptive differences in stomatal behavior evident between tomato species (see above) could reasonably be caused by changes in metabolic enzyme activity.
If at least some fundamental moral principles were self-evident, or analytic truths, or at least reasonably thought to enjoy widespread consensus or to be such that eventually all would converge on those principles, there might be some plausible candidates.
As a whole the process was fairly similar in each case – build a service in which the derived value becomes increasingly evident over time, creating a situation where any reasonably priced premium becomes trivial.
It is evident from Figure 2 that the estimates are reasonably consistent.
