Sentence examples for reasonable toxicity from inspiring English sources

These results reveal an encouraging activity with a reasonable toxicity profile in a patient population with an unfavorable prognosis.

This approach has shown considerable antitumor activity and a reasonable toxicity profile, making it an important strategy for developing new adjuvant and neoadjuvant chemotherapy regimens.

Since second-line chemotherapy for relapsed SCLC patients is a palliative treatment, a reasonable toxicity profile is essential.

In some South American countries, alcohol and water infusions have been used in patients with leukemia and breast cancer having good efficacy and reasonable toxicity at higher doses than commonly used by folk medicine [ 11- 13].

These data were consistent with one of the underlying hypotheses (namely that dose density could increase efficacy with a reasonable toxicity profile) but not the other (that sequential, full-dose therapy is superior to combination chemotherapy).

Results of induction chemotherapy followed by CRT are encouraging (Hainsworth et al, 2002; Machtay et al, 2002; Haraf et al, 2003; Vokes et al, 2003) (Table 4b) and suggest a reasonable toxicity profile, lower distal failure rates, and improved survival in comparison with historical controls using the same CRT regimen (Vokes et al, 2003).

Although the clinical trial has demonstrated reasonable and manageable toxicity in this population, the toxicity is likely to be more significant and prevalent in patients with less optimal health conditions.

6, 7 Though not yet routinely advocated, therapeutic drug monitoring is reasonable when drug toxicity or refractory fungal disease is suspected.

Rather, we would suggest interpreting the results in a positive way since at least two drugs are available for long-term use in patients with LN and have a reasonable efficacy and toxicity profile, thereby - again - suggesting that patients failing on one drug could be rescued by the other.

HERG K+ channel blockers are therefore potentially toxic, hence predicted IC50 values could provide reasonable predictions for cardiac toxicity of drugs in the early stages of drug discovery [32].

Recently, several bioavailability-based models have been shown to predict acute metal mixture toxicity with reasonable accuracy.