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In an attempt to control for these known sources of variation, it is reasonable to interrogate the clinical correlates of DNA methylation in a single subsite of HNSCC.
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While it's impossible to ask a female macaque to interrogate her feelings, it is reasonable to infer that this behaviour is similar to that experienced by human women, at least in some ways.
Furthermore, RO9021 has reasonable oral bioavailability profiles and thus can be used to interrogate the various reported biological roles of SYK in preclinical disease models.
Self interest also compellingly explains how poorly they have handled this problem to date; and why they continue — even now — to impede investigations by not disclosing enough data and/or failing to interrogate deeply enough their own systems when asked to respond to reasonable data requests.
Bach likes to interrogate stereotypes.
They called the police to interrogate her.
"We are here to interrogate you".
They're going to interrogate me.
"We wanted to interrogate our impressions.
(She does subsequently decide to interrogate me).
Hennis was a challenge to interrogate.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com