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Overall a classification of MetS exhibited poor sensitivity but reasonable specificity for the identification of IGT.
Thus, more novel tumor biomarkers with high sensitivity and reasonable specificity for ovarian cancer are urgently needed.
Magnetic resonance imaging (MRI) of the breast is a promising diagnostic technique with a high sensitivity and a reasonable specificity for the detection of invasive breast tumors [ 1, 2].
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Finally, the protective effect when conjunctivitis is used as case definition was 53% in our study, compared with 29% for human influenza based on influenza-like illness (14 ), which suggests a reasonable specificity of conjunctivitis as indicator for subtype H7N7 infection.
Abnormal wall enhancement was associated with a lower but still reasonable specificity of 71%.
We reported good sensitivity (82%) and reasonable specificity (62%) for a positive response to any of the stroke symptoms compared with a neurologist diagnosis of stroke or TIA (25).
Self-report data for hypertension has reasonable specificity (that is, few people report they have hypertension if in fact they do not), however like many other conditions, it may underestimate the true prevalence [ 19].
Faecal haemoglobin had poor sensitivity (31.0%, 15.3% to 50.8%) but reasonable specificity (90.5%, 85.6% to 94.2%) for advanced neoplasia.
The captopril renal scan can detect ARVD with high sensitivity and reasonable specificity and also gives information on the potential for blood pressure lowering following revascularization[ 11].
However, given the seriousness of meningitis, and challenges in diagnosis and management especially in resource poor regions, clinical indicators with good sensitivity, which may encourage a low threshold for performing LP while retaining reasonable specificity are desirable.
We have tried to address this difficulty by using thresholds defined by percentiles of our data, selecting a relatively high cut-off for glucose in order to have reasonable specificity and sensitivity.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com