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Indeed, such sample sizes may be required to validate and properly model biomarkers of reasonable effect size.
The determination of an appropriate sample size for an experiment is important and should be in accordance with a reasonable effect size.
However, larger group sizes in the crossover analysis (chocolate groups n = 26, capsule groups n = 36) assessing acceptability of the two treatment forms led to a reasonable effect size > 0.9.
Given the relatively short assessment period, the size of the study population, and the resulting power to detect a reasonable effect size, it is not feasible for our evaluation design to use population-based indicators, such as maternal mortality ratios and neonatal mortality rates, as outcome measures.
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Lanahan, L., McGrath, D.J., McLaughlin, M., Burian-Fitzgeral, M. & Salganik, L. 1 32, Fundamental Problems in the Measurement of Instructional Processes: Estimating Reasonable Effect Sizes and Conceptualizing What is Important to Measure (American Institutes for Research, Washington, DC, 2005).
23 We collected data on 2,132 children with diarrhea in the 2 weeks preceding the survey, which granted adequate power to detect a range of reasonable effect sizes in the logistic regression analyses of care-seeking and treatment.
All three approaches are part of our "5-steps to quit" intervention and it is reasonable to expect an effect size of at least 94% in our study.
Given the VLBW infants in this RCT were considerably smaller than those in the Anderson meta-analysis, it is reasonable to assume our effect size may be larger as serious morbidity (e.g. NEC and sepsis), poor growth, and long-term neurodevelopmental sequelae are inversely related to gestation at birth [ 2, 3]; hence, there is a much greater opportunity for human milk to improve BSID-III scores.
This is reasonable because the larger the effect size that a SNP has, the more likely it would have been discovered with genome-wide significance.
It is also assumed that the effect size is reasonable, in the sense that an effect of this magnitude could be anticipated in this field of research.
It is also assumed that this effect size is reasonable, in the sense that an effect of this magnitude could be anticipated in this field of research.
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