Sentence examples for reasonable affinity for from inspiring English sources

Pyrrolidone 15 was found to exhibit reasonable affinity for PKCδ, with lower affinity for the other isozymes tested.

Boc5 is a small molecule compound with reasonable affinity for GLP-1R and good safety profile in vivo.

Although classically defined as D2 antagonist, haloperidol has a reasonable affinity for D1R as well, 63 nM (JBC, 1986, 8397).

Taken together, these findings suggest that BNP could be exerting its proliferative effects through either NPR-A, its preferred receptor or through NPR-B, for which it has reasonable affinity [25].

XAC-AO-dansyl (20) showed a reduced but reasonable affinity.

In addition, isolated R1-6 istablele and binds to the C-terminal half of the Nav1.2_ABD with a reasonable affinity (Kd ∼2.3 µM; Figure 5B), supporting that R1-6 can function as a structural unit for Nav1.2 binding.

Though the biological activities found were generally insignificant to poor, two compounds, one of which possesses a reasonable binding affinity for mGAT1, rac-57, the other a notable inhibitory potency at mGAT4, rac-84, both displaying a slight subtype selectivity for the individual transporters, could be identified.

"It's a reasonable group that we feel an affinity for.

In the case of Tet-OFF, we assume it has the same binding affinity for Tc as TetR, a reasonable assumption if one notes that the inducer binding domain of TetR is not affected when the transactivator is added.

Since DHE displays affinity for these receptors (see Table 1), it is reasonable to hypothesize that these receptors could be involved in DHE-induced inhibition of the vasodepressor sensory CGRPergic outflow.

Mechanistically speaking, we cannot say if the decrease in the Km,dNTP is due to a higher affinity for the incoming dNTP, but this would seem to be a reasonable possibility.