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The reason of heterogeneity can be due to differences in the population or in the reference standard (CXR and CT scan).
We speculated the difference of transfusion threshold may be the reason of heterogeneity, the postulation were supported because the value of I decreased to 0 when excluded the study.
Similar(58)
Excluding one study [ 24], for reasons of heterogeneity, resulted in 8 studies with 532 children.
We further performed sensitivity analysis to explore the reasons of heterogeneity and examined characteristics of included studies.
To further explore the reasons of heterogeneity, we conducted sensitivity analyses by omitting each study one at a time.
For reasons of heterogeneity (diversity of outcome measures) only three studies were included in the meta-analyses (Hanning 1993; Kalnins 1996; Poustie 2006).
However, we assumed that both negative and positive association studies in various populations might be correct with the underlying reason of genetic heterogeneity in different populations, and possible gene-gene and gene-environment interactions [51], [52].
Probably it is the reason for heterogeneity in treatment of patients with NDPH in most case series (including ours).
The small number of studies did not allow for detailed exploration of reasons for heterogeneity using meta regression techniques.
The reasons for heterogeneity of IK1 current expression are not clear.
In fact, heterogeneity may not be entirely avoided in meta-analysis, so it is necessary for us to explore the reason and extent of heterogeneity.
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