Suggestions(3)
Exact(4)
Among survey respondents (50% response rate), the most common reason for trial registration was a publication requirement and for non-registration, a lack of familiarity with the process.
If a participant does not wish to continue in the trial, a Consent Withdrawal case report form will be completed to capture the date and reason for trial withdrawal.
During the second year, the most common reason for trial withdrawal was 'other' (e.g. participants who withdrew consent, were lost to follow-up, or moved) in the liraglutide groups and 'ineffective therapy' in the glimepiride group (figure 1).
For instance, if a newly referred patient with painful bony metastases declined participation after the initial consultation, and the phase I physician would have recommended palliative radiotherapy before enrollment into any phase I trials, the patient's refusal would be recorded as the only reason for trial non-entry.
Similar(56)
We are unable to determine the reason for trials failing to result in publication.
To investigate the frequency of interim analyses, stopping rules, and data safety and monitoring boards (DSMBs) in protocols of randomized controlled trials (RCTs); to examine these features across different reasons for trial discontinuation; and to identify discrepancies in reporting between protocols and publications.
21 There are compelling ethical and scientific reasons for trial registration.
The Quorum flow diagram illustrates the main reasons for trial exclusion.
The specific reasons for trial exit are detailed in the results section.
To address this need, our study investigated the reasons for trial participation, expectations and measures of satisfaction.
The most common reasons for trial participation were to contribute to medical science and to have improved treatment outcomes.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com