The most common reason for modification was adverse effects of GPOvir® (73.5%), followed by treatment failure (16.7%), for treatment of tuberculosis (TB) (4.2%), and pregnancy (2.7%).
Virological failure was defined as such if the physician treating the patients' HIV infection had stated virological failure as the reason for modification in the medical file.
Another reason for modification may be triggered by the fact that research practice reveals problems in interdisciplinary communication or cooperation which are not considered in the theoretical model but should, nevertheless, be integrated.
For the sake of completeness, it should be noted that there can well be other reasons for modifications, for example if there is some other dependence than a linear one for very small or very high speeds.
The database is updated annually and among other variables it contains data on: date of birth, gender, route of transmission, race, date of first HIV-1 positive test, bodyweight, immigration and emigration, date of death, date of HAART initiation, HAART regimens and reasons for modifications.
The following information was collected at each infusion: the initial infusion rate, the number and proportion of patients with an infusion modification and the reasons for modification; the number and proportion of patients who completed the 1000-mg dose; and the total infusion times among those who completed the 1000-mg dose.
Because of its severity, mucositis is a common reason for compromising modifications in dosing or treatment schedules which adversely impact tumor outcome.
It can be concluded from Fig. 10 that charge transfer should be the reason for the modification of the magnetic moment of V atom in Ag n V clusters.
MDOT's stated reason for the modification was to "reduce confusion along the US 27/US 127 corridor".
Cary, North Carolina, USA We conducted a sensitivity analysis on the definition of drug stock-out, because the reason for cART modification or discontinuation was not always noted in the medical record.
Overall, haematological toxicity was the most frequent reason for dose modification (30 patients).
