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Gastrointestinal disturbance was the dominant reason for intolerance in both groups (75% MS, 65% MMF).
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They further discuss reasons for intolerance and the evidence behind using β-blocker dose and heart rate as therapeutic targets.
Reasons for intolerance to chemotherapy included age of ≥70 years and organ dysfunction.
Clinically, decline in pulmonary function in patients was generally considered as the main reason for exercise intolerance, but definitely, SMD is a direct precipitating factor which forced COPD patients to stop activities [ 2].
6 7 Practices can exclude ("exception report") patients deemed inappropriate from the payment calculations for various reasons (for example, intolerance to a specified treatment or informed dissent by the patient).
The reasons for nonresponse or for intolerance are multiple, potentially including the development of antidrug antibodies (ADAbs) directed towards the TNF blocker.
It added: "There is also reason for concern at the intolerance to challenge displayed in the emails.
Patients who did not reach this target for any reason (gastrointestinal intolerance or contraindication to enteral feeding or repeated forced suspensions of enteral feeding because of multiple surgical procedures) were excluded from the final analysis.
Intolerance is the main reason for treatment switches, whereas discontinuation is equally explained by both intolerance and patient's wish [10].
The most common reasons for ACE-I intolerance were cough (67%), hypotension (15%), and renal dysfunction (11%).
The most common reasons for ACE-I intolerance included cough (72%), hypotension (13%), and renal dysfunction (12%).
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