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This study aimed to compare existing dosing regimens of cefaclor with recommended pharmacokinetic/pharmacodynamic (PK/PD) parameters and to see if the proposed dosing regimen could have been the reason for development of bacterial resistance.
This paper presents a systematic review the literature pertaining to the development and use of population-based health indexes with regard to reason for development of the index, geographical level of aggregation, inclusion of health indicators, weighting, sources of data and validation.
Low-density lipoprotein receptor-deficient (Ldlr −/−) mice were fed a high fat/high sugar diet to mimic a westernized diet, being a major reason for development of obesity and atherosclerosis.
Excessive use of antibiotics is worldwide the most important reason for development of antimicrobial resistance.
26, 27 The final step for management is establishing the underlying reason for development of hypernatremia.
It remains speculative what may be the reason for development of FGID after Giardia infection.
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The reasons for development of these potentially highly virulent strains remain unclear.
Major reasons for development of ARF were severe sepsis/septic shock (both groups >65% of study patients at baseline) or cardiogenic shock (please also refer to Table 1).
The reasons for development of resistance are numerous and related to antibiotic overuse and misuse in conjunction with poor infection control practices in health care settings [ 11].
Stakeholders and TB program managers in Africa should be reminded that the main reasons for development of resistance in TB are poor patient adherence to treatment regimen, inappropriate drug prescription, irregular drug supply, and poor drug quality (9 ).
Other studies have pointed out that CMV infection is one of the reasons for development of BOS [ 9, 11- 17, 19, 19, 26] yet other studies did not find that CMV infection had any impact of the onset of BOS [ 27, 28].
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