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The guiding principles of the Age of Enlightenment in the 17th and 18th centuries were to reform society using reason, challenge ideas grounded in tradition and faith and advance knowledge through scientific methods.
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Every behaviour we do is for a reason; challenging behaviour is no different.
The study can be early terminated under following considerations: - high incidence of unknown AEs or increase in known AEs with the disadvantageous proportion between risk and benefits of the proposed radiation therapy; - unacceptable high rates of SAEs; - other reasons challenging the ethical basis; - official decision.
There's no big reason to challenge the status quo, and no real force that can challenge it either.
Voters in Florida can have their eligibility challenged for any reason, and challenged voters must vote provisionally and then must present proof of eligibility to have her vote counted.
More recently, he said, he liked Mr. Hastert's leadership and saw no reason to challenge it.
It's not as if James and McNeal need another reason to challenge them.
But some opposition lawmakers see Spain's downturn as further reason to challenge the monarchy.
I never knew whether these stories were true but I didn't have much reason to challenge them.
That practice worked well throughout the prosperous 1990's, when employers paid most or all the costs, patients felt no financial pain, and doctors, who write the prescriptions, had little reason to challenge the sales pitches.
And the unwillingness of the United States to push its Israeli ally to uphold the equality of all its citizens is not only a grave disappointment, but a strong reason to challenge the United States as the leader of the free world.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com