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Fifteen shared local collinear blocks (LCBs) were determined, six of which were inverted and one of which was rearranged between CO92 and CA88 (Figure 1).
This region appears to be heavily rearranged between the porcine and human genomes.
Synteny blocks are pairs of orthologous regions which have not been rearranged between the two genomes.
Otherwise, the region was considered to be rearranged between the two species.
We also determined more precisely the extent of the fragment rearranged between the human and pig genomes.
If the above hypothesis is correct, we expect that overlapping genes should be extensively rearranged between A. aegypti and A. gambiae.
Similar(46)
Early childhood thyroid cancer cases showed significantly higher prevalence of rearrangements between the rearranged during transfection (RET) gene and the PTC3 gene (RET/PTC3 rearrangement).
These include fusion genes generated by chromosomal rearrangements between the rearranged during transfection (RET) gene and other genes, most commonly kinesin family 5B (KIF5B) and coiled coil domain containing-6 (CCDC6) [ 2- 12].
Comparison of these two maps reveals both conservation of marker order and rearranged order the between two populations.
a Regions between rearranged conserved blocks (inter-LCB) for D7S-1 are obtained from D7S-1 vs HK1651 MAUVE alignment.
Presumably there is quite some difference in the binding energy between spacing variants, due to the need of rearranging contacts between multimer units.
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