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"It is really difficult to treat a disease when you do not understand what causes it," one of the lead researchers, Prof Julie Williams from Cardiff University, said.
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Bone metastases of urothelial cancer is really difficult to handle.
Over the last decade, almost all varieties of pathogenic bacteria have become less responsive to antibiotic treatment when it is really needed, so it has become difficult to treat common infections that once readily responded to antibiotics.
"A lot of times people just wait until their acne is really bad to see the dermatologist, and at that point it becomes more difficult to treat.
They're hard to catch early and difficult to treat.
Drug-resistant infections are difficult to treat, and sometimes fatal.
While drugs can help, the condition remains difficult to treat.
But Japanese encephalitis remains incredibly difficult to treat.
After it has metastasized, it's very difficult to treat.
"Worry symptoms are notoriously difficult to treat," the study said.
Recurrent and metastatic tumors are difficult to treat.
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CEO of Professional Science Editing for Scientists @ prosciediting.com