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We are well aware that Genome-Wide Association studies (GWAs) represent a powerful tool to explore variants associated to complex traits and to evaluate possible gene-gene interactions [14], but the huge number of samples needed to reach the genome-wide threshold of significance cannot be realistically applied to an endophenotype like salt-sensitivity, which requires great care in measurement.
Layer 2 presents previous clinical applications so that the researcher can visualize situations in which the method may be realistically applied.
It is planned that the instrument will soon be revised and shortened to make it into a short, self-administrable and easy to understand tool that can be realistically applied in real clinical life.
Relevance or applicability of the results of this research depends on its generalisability, i.e. whether these results can be realistically applied to a particular group of patients in routine primary care practice [ 7].
Although in vitro oogenesis from animal and human ESCs could represent a model to study the mechanisms of oogenesis and their pathologies, the potential oogenesis from the autologous ovarian stem cells would be of great advantage because it may be realistically applied in human medicine in the future.
In this study, we critically review the current state of oxidative stress biomarkers that are used to assess the redox state of the body or specific tissues and cells in health and disease, with a focus on those that can be realistically applied to the clinic (Fig. 2).
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Getting a decent A-level grade in one of them - say a C or above - would mean you could realistically apply for a maths or science related degree with good career options, that would otherwise be barred to you.
According to this thesis, Amundsen approached the hardships realistically, applying practical lessons from his experience with Eskimos in the north and relying on well-trained dogs to pull sledges.
It's a balance between realizing you aren't the only one who feels the same way about a subject while knowing what you stand for and how to realistically apply those ideas to your life.
The notion of sustainability can only realistically be applied in a broad geophysical context, and consequently the land use planning effort might more appropriately be focussed on a regional scale.
The modelling framework proposed within a UFT context can realistically be applied to any decision-making process dealing with transport planning, especially when the complexity of the decision, the heterogeneity of the actors involved and the interaction of mixed competitive and cooperative behaviour are relevant for the implementation and the success of the plan, as in the case of UFT.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com