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This study is the first to validate the Boston BPS using "live" colonoscopies, which provides a more realistic validation of the Boston BPS.
Since Figs. 1 and 5 and their analogy is not a satisfactory evidence of their compliance with OR growth mechanism as previously explained, we decided to seek for a more realistic validation by plotting particle r3 as a function of time following Eq. (2) [41].
After realistic validation with the experimental test results, NLFEA was expanded to proposed an expression for the influence of anchored CFRP sheet in terms of bfA (25, 50, 75, and 100 mm) and LfA (100, 125, and 150 mm) on the proposed bond-slip model.
Nevertheless, it is re-assuring that the two studies that arguable employ the most realistic validation method (Fastloc GPS) obtained the most similar error estimates (Table 4; this study and [35] ).
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What will validation validate?
A crucial phase, before the successful deployment of a technology is its testing and validation under realistic operating conditions.
Seung-Ju et al.'s research discusses the passivity-based output synchronization of port-controlled Hamiltonian and general linear interconnected systems, and Casagrande et al.'s work describes a solution to the multi-machine transient stability problem and simulated validation in realistic scenarios [24, 25].
Thus, there is a lack of direct quantitative validation against realistic biological fiber architectures, and this poses an important limitation to the further development of improved FOD methods and studies which seek to apply these methods for research and clinical purposes.
Second, the application of the scoring system was tested under realistic conditions in a validation sample.
At best, they can preclude any realistic comparison of different validation experiments; at worst, they can provide misleading diagnostic information with potentially serious consequences for patient care.
Our BSSF validation suggested realistic values if compared to reports from other BoHV-1-free countries or regions that conduct full surveys.
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