Such dual ("negative" and "positive") effects of noises might be actually exploited by realistic living organisms or cells to positively facilitate some functions.
Our investigation is a significant try forward understanding the basic mechanism of external noise-induced switching in realistic yet complex organisms.
Our investigation is a significant try forward understanding the basic mechanisms of the delay induced gene switch and stochastic resonance in realistic yet complex organisms from a view of theory, and will motivate the further experimental research for gene network.
In the case that effects are detected in whole organisms under realistic exposure conditions, TIE should help to characterise and identify the cause of the measured effect.
The challenge in such models will be to relate theoretical models of the movement of the multivariate optimum to realistic expectations for actual organisms.
On the other hand, studies with caged organisms are more realistic than experiments conducted in laboratory in environmental assessment and present the advantage of using organisms with a known life history (Crane et al. 2007).
Recent examples in the literature show that engineered inorganic nanoparticles and carbon nanostructures, which may incidentally or intentionally enter into contact with living organisms, normally, at realistic doses, do not cause acute toxic effects.
The advent of second generation sequencing platforms made whole-genome shotgun sequencing of moderately-sized genomes and de novo assembly of draft genome sequences a realistic prospect for non-model organisms.
To model the metabolic dependency between the two organisms in a realistic manner, additional constraints were implemented, such that the flux of reaction i (e.g., from the mouse) and of reaction rxn C (e.g., mouse biomass reaction) were proportional (vi: vrxnC).
