Sentence examples for realistic linkage from inspiring English sources

New simulations were then performed to mimic realistic linkage disequilibrium (LD) (condition 2).

Power calculations (see online supplementary results B.6). show that, based on the current sample size and incidence of PMI, our study can detect a genotypic relative risk approximately 2 with 80% power (assuming a variant with a 10% minor allele frequency and a realistic linkage disequilibrium between the tested marker and the causal locus D′=0.8).

The genomeSIMLA [37] software was developed by merging the software packages genomeSIM [38] and SIMLA [39], [40] to simulate pedigree and case-control data with purely epistatic penetrance and more realistic patterns of linkage disequilibrium among the genetic loci.

Using a resampling approach that assumes random mating and implements crossovers as part of simulated meiosis, HAP-SAMPLE can be used to create artificial case-control samples of arbitrary size that possess realistic patterns of linkage disequilibrium and genotype distributions.

We simulated realistic patterns of linkage disequilibrium to mimic two human CEU chromosomal regions using genomeSIMLA (genomeSIM version 2.0.4 software, functionally equivalent to genomeSIMLA 1.0 for LD generation) [ 22].

Realistic data of linkage disequilibrium have been used as input source with Gene-Environment-iNteraction-Simulator2 (GENS2) to simulate gene-environment interactions and gene- gene interactions with no restriction either on the number of individual or number of non-predisposing.

Non-adjusted data might be more realistic in evaluating innovation linkages in the sectors, because most of the sectors receive some spillover effects from communication technology, even although some of the sectors do not make R&D investments in communication technology.

This process provides more consistent genetic lengths for specific linkage groups, and more realistic lengths between adjacent crossovers that represent exchange of large chromosomal regions.

These models can be tested against other more biologically realistic models to fully explore the linkages among various environmental changes, geomorphological dynamics, and biodiversity patterns.

The technique makes a linkage between GIS-based modelling and realistic panoramic video frames to dynamically augment a landscape view with modelled temporal changes.

Although the simulation of the full-sibs is not realistic in that it does not account for linkage, the aim here was to generate sets of individuals with a common level of relatedness, to allow a benchmark for comparing methods.