The network operator should manage the scheduling and the realisation of the resource measurements as well as the definition of the required thresholds for the implementation of the decision-making procedure (e.g. user satisfaction threshold, reallocation threshold).
There are also a number of functions of a health system that shape and support the realisation of the above stated goals, including resource generation and financing mechanisms, the organisation of services as well as overall regulation or stewardship [ 15].
Article 2 (1) of the International Covenant on Economic, Social and Cultural Rights (ICESCR) stipulates the right to the highest attainable standard of health, including access to medicines, is subject to progressive realisation and resource availability [ 34].
States must, however, make continuous and progressive measures to increase the realisation of the rights, depending on their available resources.
Coming from the software industry, these processes pursue the target of limiting both time-to-market and resources associated with the realisation of innovative products.
This is not mere charity on the part of wealthier countries, but is consistent with their obligation under international human rights law to provide resources to support the realisation of "core and other obligations," which includes access to ART [ 56].
The pooling of national or global patient resources should allow the realisation of prospective clinical trials (that stratify for HER2 gene amplification or EGFR expression) for patients with type II EC that may involve HER2 and EGFR tyrosine kinase inhibitors in well-defined subsets with HER2 gene amplification or EGFR expression.
In this way, the findings highlight the challenge, described in the literature on disclosing genetic findings, of balancing the benefits of disclosure to individual study participants against the resources needed to support realisation of these benefits [ 15, 45], in this case through ensuring provision of SC services, including clinical care and counselling.
It requires the state only to take reasonable legislative and other measures, within its available resources, to achieve the progressive realisation of each of these rights.
2. The state must take reasonable legislative and other measures, within its available resources, to achieve the progressive realisation of each of these rights.
