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Based on these three counts, aligned reads' weight, and reads' base probability, three scores that reflect the likelihood of a SNP at each location in the reference are generated: cSNP%: the percentage of non-match base coverage of the total coverage without counting the non-crisp coverage.
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And Delaney has been a willing competitor and even winner at times (read: weight loss, good skin).
These lists are then used to evaluate the accuracy of Slider's SNPs prediction by computing the probability of a single base mismatch to reflect a true SNP as a function of its read weight, Figure 2. We can see that mismatches that are in reads with higher weight are more likely to represent actual SNPs.
Mismatch bases (no-match): when a base in an aligned read does not match the reference base, i.e. the probability of the base in the prb file that matches the reference base is below the baseMin Prb threshold; this base is a candidate SNP. Figure 2 shows the probability of a no-match base to be a true SNP as a function of the read weight as found in two datasets.
With an alluring cover line that reads, "Lose Weight, Stay Healthy, Live Longer," the premise of this latest weight-loss regimen — or "slimming" as the British call "dieting" — is intermittent fasting, or what has become known here as the 5 2 diet: five days of eating and drinking whatever you want, dispersed with two days of fasting.
6. Define the similarity graph as an undirected weighted graph with vertices corresponding to the reads and weight of an edge connecting two reads defined as the number of anchors corresponding to the pair of reads.
Short men in bright silks quit their Foosball, Ping-Pong and pool games, and gather at the big Toledo scale that reads, "Your Weight Free".
The toilet provides a morning checkup, reads body weight, fat content and urine sugar levels and, if you want, notifies your doctor if results are amiss.
She wails miserably as she is hoisted into a blue canvas scale and then suspended in mid-air for a few seconds while a nurse reads her weight.
She wails miserably as she is hoisted into a blue canvas harness and then suspended in mid-air for a few seconds while a nurse reads her weight on the scale above her head.
Read weight: reads with a higher weight are less likely to misalign, and therefore, mismatches in the alignment of higher weight reads are more likely to be true positive SNPs, Figure 2. Crisp base match: when the read base is crisp and is equal to the reference base.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com