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The size of the bin and number of reads determine how accurately normal regions can be distinguished from those with amplifications or deletions [11], [12].
In our case, we sequence clones to relatively low coverage and from their reads determine which sets of clones overlap and in which ordering they appear along the genome.
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Hosts can import a pre-recorded ad into the show or do their own reads, determining where in the episode to place it.
Of 12,247 sequence reads determined, 10,665 and 361 were assembled into a circular bacterial chromosome and a circular plasmid, respectively.
Further analysis of sequencing reads determined that there is only one transposon insertion in the chromosome of recombinant A. marginale.
A read is an individual raw sequence of a fragment of DNA; reads can be single or, in our study, paired-end (reads determined from both ends of the fragment).
As quality scores can vary along the length of sequencing reads, determining how to trim and filter read data involves calculating summary statistics on a per column (base position) basis.
To test this hypothesis, we repeated our simulation with 50-base reads, determining the maximum number of sites that differed between the two alleles among all possible 50-base reads overlapping each differentiating site.
(To learn more, read Determining Risk and the Risk Pyramid).
(To see more on risk, read Determining Risk and the Risk Pyramid and Personalizing Risk Tolerance).
Thus, the 5′ end of a TSS contig constitutes a TSS, while the 3′ end of the longest read determines the end position of the TSS contig.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com