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We have designed and evaluated protein kinase sensors that furnish a fluorescent readout upon phosphorylation.
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Our results demonstrated that replication could serve as an epigenetic switch and that the same biological event could have different epigenetic readouts depending upon whether replication was occurring.
Upon readout completion, a beep is issued and the file is automatically displayed into a ds9 window (called "ds9spec").
The coded aperture approach allows multiple sub-frames to be coded and integrated into a single camera frame during the acquisition process, and then extracted upon readout using statistical CS inversion.
Upon later readout, such highly salient events may be erroneously interpreted to have spanned a greater period of time.
In the monkey, it was found that the termination of head movement and the subsequent maintenance of posture are centrally preprogrammed and are not dependent upon the readout of proprioceptive afference generated during the movement (Bizzi et al., 1976).
We first tested whether growth factor could activate ETK kinase activity using phosphorylation of tyrosine 40 (Y40), an autophosphorylation site by ETK upon its activation [8], as readout.
Although 4 subjects is a small sample size, we just wanted to illustrate the statistical technique, which is only dependent upon the individual's somatosensation readout from the fluctuations of the micro-movements as a stochastic process over time.
It is known that cytotoxic responses is a reflection of an integrated readout of all targets and/or biochemical pathways affected upon drug exposure [ 41].
Peter is a Bioengineering student and received his Travel Award for his recent oral presentation at the 2007 Society of Nuclear Medicine Conference entitled: "Evaluation of a new readout ASIC for a 1 mm resolution PET system based upon position sensitive avalanche photodiodes".
The readout nodes (i.e., the proteins whose activities were measured upon stimulation) are highlighted in Figure 3.
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