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Furthermore, it appeared that the effect of pyruvate treatment was independent of ROS production because there was no increase in 4-hydroxy-2-nonenal protein, a readout of lipid peroxidation [ Fig. 7 A (21)].
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Interestingly, the effect of Pkh1 and Pkh2 on deadenylation rates is observed only in synthetic media, suggesting that this regulation is an integrative readout of both lipid and nutrient availability (Luo et al. 2011).
See related research by Toufekoula et al., http://ccforum.com/content/17/1/R6 In the previous issue of Critical Care, Toufekoula and colleagues [ 1] investigated the serum and tissue concentrations of malondialdehyde (MDA) as readout for lipid peroxidation during sepsis.
Then a drop of blood onto a blood-analysis chip gives a readout of hemoglobin, thyroid hormones, blood lipids and liver function.
Notably, this readout of physiology can be readily combined with pharmacological and/or genetic tools to study the fundamentals of lipid metabolism.
The life of lipid droplets.
The continuing mystery of lipid rafts.
It also uses no fragile proteins or lipid bilayers but provides a reliable solid-state platform with only physical tools for control and readout of the DNA.
Patel, D. J. & Wang, Z. Readout of epigenetic modifications.
photomultiplier tube for readout of the scintillator.
Readout of MASE channels is multiplexed.
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