Sentence examples for readout of functionality from inspiring English sources

Since the process of senescence bypass provides an intrinsic phenotypic readout of functionality and automatically generates cell lines amenable to subsequent analysis, reverse genetics is a powerful approach to deciphering the important molecular events involved in senescence control [ 23].

Altogether our results suggest that functional biomarkers such as Caspase-8 activity as readout of the functionality of the TRAIL receptor pathway may prove superior to the analysis of protein expression, in predicting the response to IAPi+TRA combination treatment.

Together, these observations suggest that an expression signature derived from the molecular differences between p53 mutant and wildtype tumors may provide a more comprehensive and clinically useful readout of p53 functionality than mutational status alone.

Recently, the ER signature was analyzed in a cohort of ER-positive tumors and found to be prognostic of disease-free survival in patients receiving adjuvant tamoxifen mono-therapy [ 25], suggesting that a gene-expression-based readout of ER functionality may be a greater predictor of antiestrogen response than a measure based on ER protein level alone.

To address this, we first used a defined yeast-based reporter system, which detects TAp73 transcriptional activity by using as a readout the functionality of a TAp73-dependent luciferase reporter.

In order to demonstrate the pixel readout functionality of such a pixel sensor, a 2D proof-of-concept chip including a novel pixel-level signal processing chain was designed and fabricated in a 0.13μm CMOS technology.

The number of motor units in a given muscle gives a direct readout on the functionality of spinal motor neurons.

Concentric lighted rings in front of the driver display digital readouts of vehicle functions.

IDO expression by MSCs is considered as a standard readout for the functionality of the cellular product [ 75].

And this ensures a kind of functionality.

The span of functionality never changes".