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It is an electronic readout level that replaces the bubble display with a digital readout panel.
For example, as exemplified by the zinc responsive AND gated sensor (Fig. 3C), the genetic AND gate can function as a genetic filter (it filters out non specific input signals enhancing the sensing selectivity of the sensor) as well as functioning as a genetic amplifier (it increases the sensor output readout level and thus the sensing sensitivity, i.e., the signal-to-noise ratio).
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A sampling technique is given to remove Johnson noise, enabling a femtoampere level readout noise performance.
The relationship between the severity of disease in an individual and sweat chloride concentration as a readout of the level of CFTR function is complex.
Next, we stably integrated tetracycline-inducible Dll1 or Jag1 ligands fused to the Cerulean fluorescent protein, allowing us to control and read out ligand expression with the inducer 4-epitetracycline (4-epiTc) and readout the expression level by cerulean fluorescence.
Because Osk nucleates the pole plasm, which contains the posterior determinant, nanos mRNA, and the pole cell determinants, the number of pole cells provides a sensitive readout for the level of Osk activity (Ephrussi and Lehmann, 1992; Smith et al., 1992).
All of the main assays such MS-PCR, MethyLight or HM-PCR used for the detection of rare methylation in DNA samples are based on selective bisulfite-PCR amplification, but differ in the manner of data readout and the level of sensitivity [ 20- 23].
We do not believe that luciferase is an ideal readout for overall levels of transgene expression in the liver, because the levels detected are dependent on the distance from the surface of the animal.
GLI2/3 transcriptionally regulate Gli1 that serves as an effective readout of high levels of Shh pathway activation.
It is haploinsufficient and loss of one gene copy increases the haltere size, providing a sensitive readout of Ubx levels.
We used the atomic-level readout of our system to interrogate key aspects of FG Nup-TF interactions that have previously been inaccessible.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com