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Low molecular weight organic dyes have been designed and synthesized to exhibit excitation and emission wavelengths that are tuned to the excitation sources of the fluorescence signal readout instrument.
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These genosensors and the readout instruments provide a simple, accurate and inexpensive platform for patient diagnosis.
However, widespread use of these devices is hindered by their current form of separated sensors from bulky, expensive readout instruments.
A direct readout portable instrument (LeadCare Analyzer; ESA Laboratories, Bedford, MA) is also now available that can make measurements of BLLs in the field with a LOD of 1 μg/dL.
There's also a digital readout in the instrument cluster that can issue forth performance data such as lateral acceleration figures and tire pressures.
A single sided direct contact scheme through a board-to-board receptacle was developed and combined with a portable customized readout and control instrument.
For the steroid assay (n = 574), we used the instrument readout for values below the LOD; two (0.3%) testosterone values < 0.1 nmol/L, no androstenedione values < 0.3 nmol/L, no progesterone values < 0.4 nmol/L, no 17-OH-progesterone values < 0.4 nmol/L, and six (1.0%) cortisol values < 4.4 nmol/L.
The top scientists on board, Samantha Joye of the University of Georgia and Vernon Asper of the University of Southern Mississippi, peered intently at instrument readouts, hoping for a signal.
We demonstrate that by normalizing the readouts to the background reference spots present on each membrane and using specific instrument settings the readout becomes semi-quantitative and shows a strong correlation with the outcomes of ELISA.
Xpert testing was conducted per manufacturer instructions and performed using a 4-module GeneXpert (Cepheid) instrument with automated readout.
Also, the part of the forward HCAL used for the luminosity measurement is instrumented with new readout electronics, in microTCA standards.
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