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The experimental setup included three UFSD and a fast trigger consisting of a quartz bar readout by a SiPM.
This TRD architecture is based on two multiwire proportional chambers readout by a common double-sided pad read-out electrode.
Molecular imaging probes have been formulated for readout by a wide range of clinical imaging modalities including magnetic resonance imaging, computed tomography, positron emission tomography, single-photon emission computed tomography, ultrasound, and optical imaging.
Both scintillator are readout by a single pixelated photodetector based on SiPMs and the shape and intensity of the light distribution is used to identify in which scintillator the interactions occurred to allow further discrimination of the signals and subsequent quantification of this background can be utilized to have it subtracted from the raw images.
As compared to standard three MOSFET MAPS, where the charge signal is readout by a source follower, the proposed front-end scheme relies upon a charge sensitive amplifier (CSA), embedded in the elementary pixel cell, to perform charge-to-voltage conversion.
In order to reduce complexity and costs the 144 channels are shortcut in group of 4 and readout by a custom-designed 36 channels ASIC.
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The fundamental unit is a 5 cm x 5 cm gamma camera, based on the well-established Anger architecture with a continuous CsI Tl scintillator readout by an array of silicon photomultipliers (SiPMs).
In addition, further post-translational modifications adjacent to the acetylated lysine might alter the epitopes for proper readout by an antibody.
After PCR amplification, samples were then spotted onto a 384 well SpectroChip® by a robot dispenser, which enabled an automated readout by laser excitation in a compact MALDI-TOF mass spectrometer.
To match these requirements, we are designing a tile calorimeter, QCALT, where each single tile is readout by SiPM for a total granularity of 2400 channels.
A PDC capable of reducing the number of readout channels by a factor of 32 was designed and fabricated.
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