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The question of how to value different kinds of reading is complicated because people read for many reasons.
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Causes may be unknown, multiple, and interconnected... .. Teaching children to read is complicated.
Thus, in regions with dense genomic variations, the quantitative use of read counts is complicated both by an inability to align, and a difficulty of establishing the independence of each variant observation.
Unfortunately the detection of ISs is complicated wherever read lengths are shorter than the length of the IS, as is the case for platforms that are currently most widely used – Illumina and Ion Torrent.
But after that, execution is quite difficult: the long list of reads and riffs that follow is complicated.
We can measure warming by measuring temperatures; however, obtaining an accurate reading of the Earth's temperature is complicated.
In addition, mapping short sequence reads to the existing reference sequences is complicated by the inability to discern which of multiple possible repetitive loci a read corresponds.
Adding "that" after "Saturday" would help, but this sentence, too, is complicated and hard to read.
(You can read them when you're ready. Grief is complicated).
However, either method is complicated by the inherent limitations of mapping short reads.
Healthcare is complicated, because people are complicated.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com