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In starving mice, phosphoenolpyruvate carboxykinase 1 (Pck1) mRNA, known to be readily responsive to gluconeogenic stimuli, rapidly increased at 2 hours, whereas Hamp mRNA increased at 5 hours, in concomitance with a marked serum glucose decrease, and remained increased for up to 48 hours.
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Highly adaptive programs are designed to be readily responsive or adapted to the local context.
Because ESR1 is expressed primarily in the UM at postnatal day 4 5 (Korach et al., 1988), it was surprising that the UE is more readily responsive than the UM to DES exposure and showed a myriad of gene expression changes.
In addition to the novel target genes, regulatory factors (positive and negative) of the TGFβ signalling pathway were among the most readily responsive and direct target genes (feedback factors).
Divergent accounts suggested that chronic care was readily available; providers were responsive to follow-up; and correctional policies enabled patients to establish routines to adhere to their medication regimens.
This line readily formed tumours in athymic mice and was responsive to oestradiol in vivo.
This condition is usually responsive to treatment because it is readily accessible for nasal packing if bleeding does not resolve spontaneously [ 1, 2].
The screen was optimized in readily transfectable Chinese Hamster Ovary (CHO-K1) cells, which are responsive to insulin stimulation as demonstrated by the induction of AKT phosphorylation (Figure S1A).
Skunks do not readily take the raccoon ORV bait nor are they as responsive to immunization with V-RG.
The demand for products that have readily available substitutes is likely to be elastic, which means that it will be more responsive to changes in the price of the product.
To test whether our LT lines are responsive to externally provided hormones or drugs, we treated the PPARγ line with readily available agonists and antagonists (Figure 4a b).
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