Released cultures of untreated AGS readily progressed through G1 into S and G2/M phases [22], whereas 5-FU-treated cells remained in G1 phase (not shown).
Prior studies have demonstrated that RB loss can alter DNA ploidy in the presence of DNA damage, and tetraploid p53-deficient cells can readily progress to an oncogenic phenotype [57], [58], [59], [60].
The reasons for this are unclear, but as only ~50% of patients with Candida esophagitis have concurrent OPC, it is possible (and supported by our data; Figure 3) that RA patients may have elevated rates of subclinical C. albicans colonization, and hence are poised to more readily progress to clinical OPC under certain circumstances; for example, targeted anti-IL-17A therapies.
At 19 weeks after the first NNK injection when the adenoma is expected to be induced at 100% incidence and readily to progress to adenocarcinoma, mice were randomly separated into the control and EGCG treatment groups (15 per group).
Yamada, along with Fisheries Agency Counselor Joji Morishita and Assistant Director of the Far Seas Fisheries Division Toshinori Uoya, readily acknowledged that progress in talks in Santiago presented an opportunity to move forward in the IWC.
Each branch works to make the records of human progress readily available, and the contribution of each to society can only suffer from the lack of integration into a larger whole.
Whereas acute osteomyelitis subsequent to bone trauma or a surface wound infection may be readily diagnosed, slowly progressing chronic osteomyelitis derived from hematogenous sources often presents a more difficult diagnosis [1],[2].
This is in accordance with the view of TPACK as a holistic and transformative form of knowledge suggesting that growth in just one of the three knowledge bases, i.e., technology, content, and pedagogy, does not readily bring about progress or growth in TPACK as a whole (Angeli & Valanides, 2009).
Specifically, when embarking on a new journey or working toward a specific goal, fear can readily derail our progress.
Although many gold intermediates are highly reactive to be readily isolated, some progress has been achieved in the observation of a few key species.
