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Nonetheless, at high proximity, activated neutrophils will counter these activities of AAT by the release of oxidative radicals; these will readily neutralize the inhibitory capacity of AAT [ 108].
Phenolics are water-soluble antioxidants which readily neutralize ROS by donating their hydrogen atoms and are especially important because of their prevalence in plants and the significant contribution they make to water-soluble antioxidant activity [ 5].
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This may reflect that gH alone is more readily neutralized than gH/gL.
Although the replacement of NAg3a in these recombinant viruses could result in partial antigenic changes, as shown before [18], [20], the overall type 3 antigenic structure was not significantly altered since all virus isolates were readily neutralized by type 3 polyclonal serum.
Here, we demonstrate that the supernatant derived from ovarian ascites at 2.5% readily neutralizes Ad5 infectivity by up to 3 logs.
The MDA-MB-231 cells were more sensitive to growth inhibition with the AGR2-neutralizing mAb than were T47 D and ZR-75-1 cells, although this may be trivially explained by the observation that MDA-MB-231 cells have significantly lower levels of AGR2 than do T47 D and ZR-75-1 cells used in the same experiment and thus may be more readily neutralized.
A pervasive misconception in the biological literature is the ability of the thiol group of glutathione to readily intercept and neutralize almost any electrophilic species with high efficiency.
The AGA report says that 70% of the 61 million people in the U.S. who suffer from heartburn can get relief from readily available antacids (Tums, Rolaids), which neutralize stomach acids, and the so-called H2 receptor antagonists (Pepcid AC, Tagamet HB and Zantac 75), which reduce production of stomach acids.
In contrast to lymphoid cells or neutrophils, anuclear platelets were insensitive in vitro to both silvestrol and HHT under conditions where the BH3 mimetic compound ABT-737 readily killed platelets by neutralizing the anti-apoptotic Bcl-xL.
The fact that NAC, another thiol and a nontoxic GSH-prodrug, did not protect the cells as efficiently may be explained by the fact that it is readily accepted by the cells, while GSH is not, thus leaving GSH outside the cell to neutralize the CS-attacking aldehydes (Gmunder et al, 1991).
"It helps neutralize their speed.
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