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Here we report that both DNA- and vaccinia-based vaccines encoding SIVmac239 gp160 readily elicited high levels of CD4i Abs in experimental animals.
HIV-1 has evolved multiple mechanisms to evade readily elicited antibodies against more open Env conformations.
Additionally, further characterization of the virus inhibitory capabilities of anti-HIV-1 antibody isotypes can define the spectrum of potential protective HIV-1 antibodies that could be readily elicited by experimental vaccines and adjuvants.
Thus, small molecules like the DMJ compounds may be useful as microbicides to inhibit HIV-1 infection directly and to sensitize primary HIV-1 to neutralization by readily elicited antibodies.Preventing HIV-1 transmission is a priority for global health.
These risk factors are readily elicited through history taking and measurement of body temperature.
Three readily elicited clinical risk factors were identified to help detect children at risk of neurological involvement.
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Based on the structure complex, we posited that synthetic derivatives of the Rv3 oligosaccharide might be designed to more fully mimic mammalian oligomannose and, consequently, more readily elicit cross-reactive antibodies.
With regard to single people, though, direct questions readily elicit negative judgments.
With a preimmune repertoire filled with autoreactive precursors, drive by autoantigen may more readily elicit a specific response [ 16].
These data suggested that raloxifene mediated cell death is dependent on the presence of steroids as higher concentrations of raloxifene are required to readily elicit potent cytotoxicity.
Worthy of note is that experimental induction of LPS-related emesis is achieved by intravenous or intraperitoneal routes [ 122- 127], whereas SEs readily elicit vomiting when administered intragastrically [ 124, 128].
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