Although a greater TSH rise may be seen in some microTSHomas, the response is still attenuated and readily distinguished from the more exuberant TSH response of TRβ RTH patients (typically greater than 5-fold, Koulouri, Moran, Halsall, Chatterjee and Gurnell, unpublished observation).
Our specific focus is the evolutionary stability of attenuation whether the attenuated virus will readily evolve to greater fitness across tens to hundreds of generations of adaptation.
LLINs or IRS are clearly insufficient in themselves to eliminate malaria transmission because de facto protective coverage is attenuated where mosquitoes can readily access blood resources from animals or from humans while they are outdoors (figure 1 c) [ 1– 4, 12, 20, 21].
When modified on the surface of nanocarriers, those peptide ligands would readily degrade and the targeting efficacy is significantly attenuated.
To our surprise, this screen identified only 89 attenuated mutants with disruptions in a total of 64 genes, whereas the majority of the attenuated mutants in the OM model were readily detectable in the output pools from the nasal lavages (Fig. 3B; Table S1).
However, these methods may not be readily adaptable in more turbid situations where fainter signals are attenuated and variability in intensities are high.
The low regioselectivity, however, can be readily explained again by the polarization caused by the inductive effect, which in this case was attenuated by the opposing inductive polarization by the BnO group.
Everything is attenuated.
It is now dangerously attenuated.
So its startle reflex is not attenuated.
