Importantly, Lys-plasminogen is more readily activated by plasminogen activators as compared to Glu Plg.
Consistently, the promoter regions A2, A3 and C, lacking AP-1 binding sites (Supplemental Fig. S1), were readily activated by Nter-142Q (Fig. 3), likely by the activity of transcriptional factors other than AP-1.
Compared with A549 cells, BDNF had no effects on Pyk2 and ERK activations or the invasion of HBE cells, which suggested that in TrkB-positive A549 cells, up-regulated TrkB was readily activated upon BDNF, and signaling pathways initiated by TrkB led to an immediate activation of Pyk2 and Pyk2-mediated functions.
Most schools also request parents' e-mail addresses at the start of the year, which some use to create an e-mail database that can be readily activated to send urgent or routine notices.
We find that slip systems with large interplanar distances are readily activated, which agrees well with experimental observations.
It remains debatable, and largely unclear, whether this also results in a more readily activated trigemino-vascular system, and is therefore sufficient to explain the headache.
It appears that these patients may have an increased number of microglial cells, which are primed and can be readily activated in response to a mild stressor [25].
Human NK3.3 cells can be readily activated via CD4zeta-based CARs to target both tumor and virus-infected cells, demonstrating early evidence that CAR-modified NK cells have the potential to be used to treat HIV infection.
This was evident in the GPU load demand, which increased steadily with increasing node count but remained below 100%, while the CPU was readily activated to maximum load for even simple models.
