Since SEQuel builds the positional de Bruijn graph on only the set of reads that permissively align to a single contig (and not the complete set of reads), the complexity caused by erroneous k-mers being recruited from other regions in the graph is eliminated.
Music is not the same as books, not least because the structure of music sales, ie album vs single, is different; use cases are different, ie 100s of plays vs single or few reads; and the complexity of digitising non-digital sources is different, ie ripping a CD vs scanning, OCRing, proofreading a book.
The President was not universally trusted in the black community; indeed, Taylor Branch's Pulitzer Prize-winning book, Parting the Waters: America in the King Years, was required reading to better understand the complexity of the era.
However, this problem has been resolved by the use of the de Bruijn graph which models overlapping sequences rather than reads, thereby reducing the complexity of dealing with multiple reads [ 25- 27].
Understand the complexity of praying.
I especially love reading about the complexities of relationships (all sorts) and different kinds of love.
Artyomenko, A. et al. Long single-molecule reads can resolve the complexity of the influenza virus composed of rare, closely related mutant variants.
The genome was assembled using the software package DeNovoMAGIC2 (NRGene, Nes Ziona, Israel)11,12 software (Supplementary Information 2.2), which is a DeBruijn graph-based assembler designed to efficiently extract the underlying information from raw reads to solve the complexity of the DeBruijn graph because of genome repetitiveness.
Short reads, while increasing the complexity of the problem because of higher mapping ambiguities, did not have a negative effect on our method's performance.
As someone who has both suffered from and studied depression (I am trained as a cognitive-behavior therapist, and my master's was on depression), I found it refreshing to read something that acknowledges the complexity of this mood disorder.
