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As shown in Fig. 1 A, BCVA decreased from 31.6 ± 5.1 at baseline to 28.8 ± 11.6 letters read at week 16 in eyes treated initially with placebo and subsequently increased to 35.4 ± 11.2 letters read at completion of infliximab treatment (week 32).
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The optical density (OD) was read at 450 nm within 60 min from the completion of the reaction.
In contrast, visual acuity improved from 23.5 ± 10.3 at baseline to 30.4 ± 13.4 letters read at week 16 in eight infliximab-treated eyes and was sustained at completion of placebo treatment (31.4 ± 12.1 letters read).
On completion of the assay the plate was read at an absorbance of 450 nm (0.1sec) using a Victor2 plate reader (Perkin Elmer, Dublin, Ire).
On the other hand, BCVA increased from 23.5 ± 10.3 at baseline to 30.4 ± 13.4 letters read at week 16 in eyes treated initially with infliximab and remained essentially unchanged at completion of placebo treatment (31.4 ± 12.1 letters read, week 32).
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CEO of Professional Science Editing for Scientists @ prosciediting.com