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This kind of production system is more sophisticated than conventional manufacturing chain (as cellular manufacturing system) and can decrease the reactivity time and new products can be quickly introduced (as for dynamic cellular manufacturing system).
* Mean ± SD Age, previous severity of illness (APACHE II score), GCS and abnormal pupil reactivity, time to BD and hypothermia constitute the most important factors that differentiate the two categories.
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However, this study differed significantly in the methods used to assess microvascular reactivity, times of endpoint analysis, and, notably, the design of control arms.
The Wilcoxon signed-rank test was performed to evaluate whether there were significant differences between 50 mA ML-SSEP, EEG reactivity appearance time, and time of best motor response among patients who had 10 or 50 mA ML-SSEP or EEG reactivity.
To provide adequate analysis of these single sera and also for paired sera that were reactive but did not demonstrate changing levels of reactivity with time, a competitive rPA inhibition ELISA (CI-ELISA) was developed based on the qualified anti-PA ELISA.
These pre-RA studies also showed increased ACPA reactivity in time periods closest to disease diagnosis and an expansion of the ACPA repertoire over time among cases.
Variability of individual platelet reactivity over time in patients treated with clopidogrel: insights from the ELEVATE-TIMI 56 trial.
However, loss of reactivity over time, due to a build up of corrosion products or other precipitates on the iron surface, is a great concern.
The second mechanism reduces the specific surface area down to a few m2 g−1—whish is typical for an industrial quicklime and severely reduces its reactivity: the time to react with water is around 15 min.
The extent of individual mechanisms varies with operational parameters (e.g., amount of Fe0, Fe0 intrinsic reactivity, residence time, age of the Fe0 filters).
Both functionalized Fab' were then mixed 1 hour or1 month after production to obtain BsAb in order to validate their stability and their reactivity over time.
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