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Following initial mechanistic studies, Lectka and co-workers speculated that addition of a second Lewis acid may coordinate NFSI selectively, thereby increasing its electrophilicity and reactivity (Scheme 70).
Thus, strongly σ-donating and weakly π-acidic ligands, such as NHCs (N-heterocyclic carbenes), MICs (mesoionic carbenes),[ 19] or CAACs (cyclic (alkyl)- (amino carbenes)[ 20] are expected to increase the carbene-like reactivity (Scheme 5).
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For each technology option, we give an overview of the technical parameters, reaction pathway, reactivity, procedural scheme, and laboratorial and pilot devices.
We postulated that readily generated 4 might provide the right balance between kinetic reactivity and selectivity (Scheme 2).
This reactivity is illustrated in Scheme 4.
Finally, we have preliminary results pertaining to the reactivity of these hemiaminals (Scheme 2).
They found that several of the catalysts in this family were effective and that the hydroxyl group of the cinchona alkaloids was important for the high reactivity of the transformation (Scheme 135).
This paper studies the fuel cycles and shuffling schemes of the fuel assemblies of the sub-critical assembly to preserve the system reactivity and the neutron flux level during the operation.
Considering dehydration products containing a Michael acceptor in the overall scheme of secosterol reactivity introduces the previously unrecognized possibility of protein modification at histidine side chains.
In some of our work on carbon dioxide activation we have shown that the trans influence of the aryl group plays a large role in instilling reactivity in the X-group (Scheme 1).
Five pieces of experimental evidence suggest the potential involvement of secosterol dehydration products in the overall scheme of secosterol reactivity: (1) Seco A loses a water molecule in the presence of catalytic N-acyl lysine, forming a dehydration product upon incubation at 37 °C.
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