The design, synthesis, and in vitro biochemical evaluation of a class of mechanism-based inhibitors of human leukocyte elastase (HLE) that incorporate in their structure a 1,2,5-thiadiazolidin-3-one 1,2,5-thiadiazolidin-3-one 1,2,5-thiadiazolidin-3-one 1,2,5-thiadiazolidin-3-one 1,1o it is dioxideed.
Concepts of hard soft acid base (HSAB) interactions allow estimating chemical reactivity of elements, such as electronegativity, i.e. the chemical potential changed of sign, hardness and electrophilicity.
Next, various aspects of SMR designs such as: fissile material inventory, core-life, refueling, burnup, digital instrumentation and controls, underground designs, sealed designs, enrichment, breeders, excess reactivity, fuel element size, coolant opacity, and sea-based nuclear plants are discussed in the context of proliferation concerns.
The reactivity of the elements, especially yttrium, is not always obvious due to the formation of a stable oxide layer, which prevents further reactions.
Since chosen compounds vary in metal oxidation state and in X element, reactivity of differently coordinated surface O is studied as a function of different parameters such as coordination number, geometrical and chemical environment.
Here, we examined the cross-reactivity of RSII elements with PatA-like proteases.
The discovery of new reactivity modes of underexplored elements underpins major advancements in synthesis.
A key feature of these methods is that the structural elements and reactivity driving the peptide macrocyclization process are built into the genetically encoded polypeptide precursor.
They determine the chemical reactivity of each individual element, or its equivalence in the case of a complex system of elements or compounds.
The process of audio recording conversations may have introduced an element of reactivity as participants were aware that their conversations were being recorded.
The C4F6 antibody was raised against apo-G93A and has been shown to have specific reactivity to this sequence element (WT SOD1, FALS mutants other than G93A, and SOD1 with other substitutions other than alanine at position 93 show little reactivity to C4F6 when denatured).
