When this peptide sequence was inserted into the extracellular domain of epidermal growth factor receptor (EGFR), this reactive sequence directed the specific labeling of EGFR in live mammalian cells.
The truncation and mutagenesis study of the most reactive sequence identified, R1 4, revealed that the microenvironment effect is likely due to the selective recruitment of the aryl palladium complex via noncovalent interactions such as π π and hydrogen bonding interactions, which may facilitate the assembly of a key intermediate along the reaction coordinate.
Also on display are Nils Hackey and Jason Krugman's sound reactive light installations which are composed of 42 work lights programmed to project different sound-reactive sequences.
S. citri BR3-3X showed probe-reactive sequences in both the chromosomal and extrachromosomal DNA fractions.
As a first approximation, this approach reduces the number of potential cross-reactive sequences identified and makes experimental validation feasible.
In reality, however, TCRs are not required to recognize HLA-bound peptides by sequence similarity but rather by peptide side chain accessibility., Consequently, the set of potential cross-reactive sequences is very likely dramatically greater and would be unwieldy in initial validation experiments.
In this work, we obtain and compare the control properties of thermally coupled reactive distillation sequences and thermally coupled extractive distillation sequences with those of conventional reactive and extractive distillation configurations.
Compared to the naïve G4 sequence, the most reactive peptide sequence R1 4, GRYFSΘPRPSR (Θ = Hpg), gave greater than 5-fold enhancement in kinetic constant when measured in fusion protein context.
In this work, reactive distillation sequences with different degrees of integration are investigated with the aim to identify the optimal configuration.
An alternative approach is allogeneic TCR gene transfer, in which tumour-specific T cells are isolated from a patient experiencing tumour remission and the reactive TCR sequences are transferred to T cells from another patient who shares the disease but is non-responsive (Gao et al., 2000; de Witte et al., 2006).
The reactive site sequence of mEndopin 1B is somewhat different from that of mEndopin 1A.
