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The most chemically reactive portion of fatty acids is the acidic carboxyl group (COOH).
Because of their preponderant weight in the glyceride molecules and also because they comprise the reactive portion of the molecules, the fatty acids influence greatly both the physical and chemical character of glycerides.
Lecithin could increase partitioning of the reactive portion of α-tocopherol into the water phase, which could make tocopherol a more efficient free radical scavenger (Laranjinha and Cadenas 1999).
CTG contains a thiol reactive portion, which undergoes a glutathione S-transferase-mediated reaction within the cytoplasm of the cell, making it impermeable to cell membranes, thereby trapping the fluorescent tracer within the cell.
The notion that the reactive portion of the DHQ ring might pivot away from Lys170 falls in line with recent docking/molecular dynamic experiments, which, performed using the closed β8−α8 loop conformational state as a starting model, identified a stable binding mode for DHQ, similar to its position in the K170M structure but differing in that the 3-carbonyl has rotated away from Lys170.
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In this sense, biotin derivatives may be prepared, which contain reactive portions able to couple with particular functional groups in proteins and other molecules.
These results indicate that the fraction of OM relatively resistant to chemical oxidation (presumably strongly bound to reactive portions of mineral surface) appeared to contribute to the inhibition of RCs adsorption on 2 1 interlayer sites.
The most reactive portions of ferrihydrite and nanogoethite in glacial and iceberg-hosted sediments from Antarctica have been estimated by an ascorbate extraction which dissolves 0.10 ± 0.11% Fe from iceberg and glacial sediments.
Traditionally, cytotoxic drugs have undergone chemical conjugation to mAbs, whereby reactive portions of native amino acids are made to interact and bind a specific part of the linker molecule [ 134].
These include (1) the M20 and FG loops, which change their position during the catalytic cycle in WT Ec-DHFR, (2) the binding domains that surround the adenosine ring of the NADPH cofactor and the polyglutamate tail of the DHF substrate, and (3) a region of protein which includes active site residues near the reactive portions of NADPH and DHF.
Thus, while a reduced memory B compartment has been reported in cancer patients, we show that a melanoma-reactive portion of this compartment remains in our patient cohort.
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