The indolequinone structure in the pro-drugs was designed to have an open reactive point at the N-1 position offering the possibility of further conjugation with macromolecules to modify the bio-availability of these pro-drugs in vivo.
However, when we extended the time of the chemical exposure, some films revealed an apparent reactive point with a molecular weight of approximately 250 kDa.
Via positive feedback effects these dependencies lead to the instability of the process in a range of reactive working points of the so-called transition mode.
These two vectors combine to define what we call the reactive difference point composition.
Another important aspect is the shift of deposition parameters and reactive working point due to target erosion.
We show that there only certain feasible topologies of the RCPM and these depend only on the position of the reactive difference point composition.
Using the proposed vector notation and the reaction difference point, we provide a simple and visual explanation for the term 'reactive azeotrope', herein referred to as a reactive fixed point.
We look at a simple example where the vapour liquid equilibrium (VLE) is ideal and show that we can classify regions of reactive difference point compositions that result in similar topology of the RCPM.
A series of reactive pour point depressants (PPD) with anhydride group were prepared, and their action mechanism had been investigated by Fourier transform infrared spectroscopy (FTIR), differential scanning calorimeter (DSC) and cross-polarized light microscope.
It therefore enables us to investigate the stability of the reactive working point and to simulate the operation of a reactive gas control loop in the unstable transition mode.
